Recorded BioBasics 101: The Biology of Biotech for the Non-Scientist

BioBasics 101: The Biology of Biotech for the Non-Scientist offers a fascinating exploration of the fundamental scientific principles that underpin the life sciences. It delves into the crucial roles of the FDA, NIH, academia, and drug sponsors and how they interact to promote scientific breakthroughs. It thoroughly explains the biological foundation of cells, DNA, RNA, and proteins, uncovering their applications in biopharmaceuticals. Building on this foundational knowledge, BioBasics 101 details the genetic basis of diseases, highlighting the devastation of mutations and the impact of genomics and proteomics on personalized medicine. This course culminates with a survey of immunotherapies, which sets the scene for BioBasics 201, a follow-on course that expertly examines all therapeutic drug classes. Get ready to revolutionize your understanding of the life science industry in this interactive course―register today!

Week 1 : Industry Overview

Explore the diverse healthcare industry sectors, industry hubs, and associations, while delving into the relationships between the FDA, NIH, academia, and industry. Discover the pivotal role of research support companies and funding sources in the healthcare landscape.

Week 2: Biology: The Basis of Biopharma

Uncover the foundations of biotechnology, from essential life molecules and cell structure to industry applications like drug targets and addressing mitochondrial diseases. Explore the vital role of cell signaling, with a specific focus on its application in understanding and combating cancer.

Week 3: DNA: Biopharma's Blueprint

Learn more about the  blueprint of biopharmaceuticals by tracing the history of DNA discovery and exploring its structure and organization. Discover how DNA codes for proteins and its critical role in replication. See how these principles are applied in the industry, from detecting chromosome abnormalities to advancing pharmacogenomics and PCR technology.

Week 4: Proteins: Biopharma's Workhorse

Uncover the role of proteins as the workhorses of biopharmaceuticals. Learn how DNA codes for proteins and explore chaperone therapeutics, post-translational modifications, gene expression, and epigenetics. Discover their crucial applications in pharmacological chaperones, biologics, drug discovery, and epigenetic medicines within the industry.

Week 5: Genetic Engineering

Explore  into the world of Genetic Engineering, exploring key concepts like plasmids, restriction enzymes, and recombinant DNA. Learn how these techniques are used to create recombinant proteins and discover their applications in pharmaceutical animals, plants, and healthcare.

Week 6: Genetic Basis of Disease

Learn more about Genetic Basis of Disease, focusing into alleles, phenotype, genotype, and the role of dominant and recessive genes. Explore mutations, their causes, and their connection to genetic variation and disease. Discover how genetic insights are applied in precision medicine, including companion diagnostics, with real-world examples like HER2+ and Herceptin.

Week 7: Genomics: Understanding the Genetic Basis of Disease

Get to know Genomics to unravel the Genetic Basis of Disease. Explore genomics, non-coding DNA, and how mutations are identified in both common and rare genetic diseases. Learn about cutting-edge techniques like DNA microarrays and third-generation gene sequencing, and discover how genomics shapes personalized medicine and comparative genomics applications.

Week 8: Drugs Mitigate Disease: An Overview

Gain a comprehensive overview of Disease Mitigation through Drugs. Explore various drug categories, from small molecules and antibiotics to biologics, vaccines, therapeutic antibodies, and cutting-edge treatments like gene therapies, immunotherapies, cell therapies, and stem cell therapies.

Five Takeaways

 

  1. Master the essential terminology of the life science industry.
  2. Identify the crucial roles of the FDA, NIH, academia, and research support companies and state how they work together to promote scientific breakthroughs.
  3. Describe DNA, RNA, and protein structure and function and explain how these molecules interact in healthy and diseased tissue.
  4. FDiscuss the genetic basis of diseases and the impact of genomics and proteomics on personalized medicine.
  5. List types of immunotherapies and summarize how each mitigates disease.

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