The Science of Molecular Diagnostics is a one-day course exploring the growing role of molecular diagnostics within healthcare. Participants will learn about a range of diagnostic tests, focusing on molecular diagnostics. The basic science that these diagnostics rely on will be described, including PCR, next-generation DNA sequencing, microRNA, DNA, proteins and antibodies. The class will also include a discussion of related ideas such as biomarkers, pharmacogenomics, and companion diagnostics. Learn to more effectively manage current and emerging diagnostic technologies.

Diagnostics Overview 9:00–9:45
Diagnostic Defined
Uses of Diagnostics
Types of Diagnostics
Biomarkers

Science of Moelcular Diagnostics:
DNA & Proteins
 9:45–10:45
DNA Structure & Function
Chromosomes & Genes
How DNA Codes for Proteins
Protein Structure & Function
The Proteome
Lab: DNA Isolation & Extraction

Break 10:45–11:00

Genetic Variation:
Basis of Disease 11:00-12:00
Alleles
Mutations: Genetic Variation
Genetic Basis of Disease
Personalized Medicine & Diagnostics
Activity: Genetic Variation of Taste

Lunch 12:00-1:00

DNA-Based Diagnostics 1:00–2:30
Polymerase Chain Reaction (PCR)
Reverse-Transcriptase PCR (RT-PCR)
DNA Microarray & SNP Chips
Next Generation Sequencing
From Big Data to Rare Disease
Third Generation Sequencing
Activity: Microarray for Determining Drug Metabolism

Break 2:30–2:45

Protein-Based Diagnostics 2:45–3:45
Antibodies
Enzyme-Linked Immunosorbant Assay (ELISA)
Multiplexed ELISA
Bead Immunoassay
Lateral Flow Immunochromatographic Assay
Protein Chromatography

Liquid Biopsies 3:45-4:15
Cell-Free DNA
Exosomes & Nucleosomes
Circulating Tumor Cells

Q&A|Review 4:15–4:30


  • Want In-House? | Let’s Chat
  • Deliverables | Course Book, Certificate of Attendance
  • Open Enrollment | FAQ
  • Need Help | Contact Us T. 410.377.4429